Novabone Dental Putty Cartridge Form Resorbable Bone Graft Material

NovaBone Dental Putty is a new, next-generation Calcium-Phosphosilicate bone graft material based on NovaBone’s bioengineered technology platform that offers enhanced handling characteristics with unparalleled performance.

NovaBone Dental Putty is ready to use and extremely user-friendly. It is pre-mixed, cohesive, moldable, and adaptable. Dental Putty truly revolutionizes bone graft substitutes with its proven ability to accelerate bone regeneration.

NovaBone Dental Putty is stable at room temperature, does not require refrigeration, has a 4-year shelf-life, and appears radiodense on radiographs.

Unique Formulation

NovaBone Dental Putty is 100% synthetic and fully resorbable. It is composed of calcium phosphosilicate (CPS) particles in a bimodal size distribution combined with a polyethylene glycol and glycerine binder.

The binder improves handling and aids in maintaining the space between the particles, which facilitates revascularization after implantation.

The bioactive CPS component makes up 70% of the putty by volume. Upon implantation, the water-soluble binder is absorbed within 24 to 72 hours, creating a 3-dimensional porous scaffold that facilitates diffusion of blood and tissue fluids through the matrix. The smaller CPS particles (32-125 μm) are more rapidly resorbed, providing the initial burst of Ca and P ions. Subsequently, the larger particles (90-710 μm) react, and being more resistant to resorption, continue the process of bone regeneration.

Smart Science

Unlike most synthetic grafts that are only osteoconductive, bioactive NovaBone® Dental Putty also has an "osteostimulative" effect. After implantation, surface reactions result in absorption of the graft material, a controlled release of Si, Ca, and P ions, and concurrent new bone formation.

These surface reactions result in an osteostimulative affect, defined as the stimulation of osteoblast proliferation in vitro as evidenced by increased DNA content and elevated osteocalcin and alkaline phosphatase levels. In vitro gene array analysis has confirmed that when human primary osteoblasts are exposed to extracts of CPS, upregulation of several gene families occurs.

Features :-

Superlative Handling

• No mixing is required. Putty can be placed directly into the defect.

Completely Resorbable

• Putty resorbs completely and gets replaced by bone. Re-entry time is about 4-5 months and is dependent on the size and site of the defect

Retention & Adaptability

• Putty stays together after placement and irrigation. It is moldable into different shapes and adapts well to the defects and implant surfaces

Osteostimulation

• Putty exhibits enhanced bone regeneration rates compared to other bone graft substitutes by a unique phenomenon: Osteostimulation

Storage & Shelf Life

• Putty does not require special storage conditions. It can be stored at room temperature. 4-year shelf life.

Key Specifications :-

Indications :

Although approved for use in most indications, NovaBone Dental Putty is best for use in crestal and lateral sinus elevation, immediate implants, partial extraction therapies, socket preservations and periodontal defects.

• Socket Management
• Periodontal Defects
• Crestal Sinus Elevation
• Immediate implant Surgeries
• Cystic Defects - Apicoectomies
• Cranio-maxillofacial defects (CMF)
• Ridge Augmentations (in combination with morsels)

SIZES & AVAILABILITY

NovaBone Dental Putty is available in multiple delivery options: trays, pre-filled syringes and a unique cartridge delivery system. The diameter of the cannula is 2.8mm which is ideal for dispensing of the graft, especially in minimally invasive techniques such as gaps in immediate implant and crestal approach sinus lifts. Cartridges are available in various sizes and are used in conjunction with cartridge dispenser.

Packing

• Novabone Dental Putty Mini Cartridge - Bio Graft 1 X 0.25cc
• Novabone Dental Putty Mini Cartridge - Bio Graft 4 X 0.25cc
• Novabone Dental Putty Cartridge - Bio Graft 1 X 0.5cc.